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The presentation of cluster headache is classic. Cluster headache consists of attacks of severe, strictly unilateral pain in and around the eye and/or temporal region. This temporal, periorbital pain is frequently confused with a masticatory or dental pain. The attacks may last from a few minutes to as much as 3 h. The attacks occur from once every other day up to eight times per day. They arc associated with one or more of the following: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, forehead and facial sweating, miosis, ptosis, and eyelid edema. Attacks occur in series lasting for weeks or months. These are the so-called cluster periods. These periods are separated by periods of remission, which may last months or years. Cluster headache predominately affects men in a ratio of 5:1 to women. This is in contrast to migraine, which predominately affects women in a similar ratio. Differential diagnosis of cluster headache includes dental infection and acute pain of the masticatory musculature.